Protein Alignment lbm and CD37

DIOPT Version :9

• Sequence 1: NP_001260757.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 61/272 - (22%)
• Similarity: 96/272 - (35%)
• Gaps: 87/272 - (31%)

  Fly     8 VKIASIVLNAVLGFLAAGAI----G-WIAYNADTETEEFVIAAYIACSL-----------ILVFA 56
            :|....|.|  |.|...|::    | ||..: .|....||..|::...:           .:..|
Human    11 IKYFLFVFN--LFFFVLGSLIFCFGIWILID-KTSFVSFVGLAFVPLQIWSKVLAISGIFTMGIA 72

  Fly    57 LLGIFAAIRESVVLTATSAVFLLILAILQI-----VSTCLFLHEFDVKSGRDMVEVAWQ------ 110
            |||...|::|...|.......||:|...||     :||.....|   :|.||:||...|
Human    73 LLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLE---RSLRDVVEKTIQKYGTNP 134

  Fly   111 -----ANNMDSLQQKHECCGQSSAQDYIHLSLL---------IPPSCY----------------- 144
                 ..:.|.:|.:..|||....||:..:.:|         :|.|||
Human   135 EETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDKVILP 199

  Fly   145 --------------ADLQQTP--DHLYLDGCIEKVQSFYESDKLRFIIVSWVLVAFELICFALAV 193
                          ||:...|  .|:|.:||.:.:|.:..::.:..:.:...:...|:....|:|
Human   200 QLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICLGVGLLEMTVMVLSV 264

  Fly   194 FLAISFKNKQRR 205
            .|       |||
Human   265 QL-------QRR 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbm	NP_001260757.1	Tetraspannin	8..198	CDD:278750	58/263 (22%)
		tetraspanin_LEL	<109..169	CDD:239401	21/112 (19%)
CD37	XP_005259492.1	Tetraspannin	26..269	CDD:278750	54/253 (21%)
		CD37_CD82_like_LEL	108..243	CDD:239413	29/137 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810