Protein Alignment lbm and TSPAN18

DIOPT Version :9

• Sequence 1: NP_001260757.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 55/255 - (21%)
• Similarity: 95/255 - (37%)
• Gaps: 69/255 - (27%)

  Fly     2 GCATTSVKIASIVLN--AVLGFLAAGAIG-WIAYNADTETEEFVIA-------AYIACS---LIL 53
            |...:.:|....|.|  ..||.....||| |:..: .|...|.|.|       |||..:   |:.
Human    13 GDCLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVD-PTGFREIVAANPLLLTGAYILLAMGGLLF 76

  Fly    54 VFALLGIFAAIRESVVLTATSAVFLLILAILQIVSTCL-------FLHEFDVK---------SGR 102
            :...||...|:||:..|.....:|:||:.:.::.:..|       ...||..|         :..
Human    77 LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHYQGNNDT 141

  Fly   103 DMVEVAWQANNMDSLQQKHECCGQSSAQDYIHLSLL---------IPPSCYADLQQTPDHLYL-- 156
            |:....|     :|:.....|||.:..:|:...|:.         :|.:|.....|:.|.:.|
Human   142 DVFSATW-----NSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRDGVLLSR 201

  Fly   157 -------------DGCIEKVQSFYESDKLRFIIVSWVL----VAFEL--ICFALAVFLAI 197
                         .||...:.:.:|:    ::.::..|    :|.||  :.||:.:|..|
Human   202 EECLLGRSLFLNKQGCYTVILNTFET----YVYLAGALAIGVLAIELFAMIFAMCLFRGI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbm	NP_001260757.1	Tetraspannin	8..198	CDD:278750	54/249 (22%)
		tetraspanin_LEL	<109..169	CDD:239401	14/83 (17%)
TSPAN18	XP_005253274.1	Tetraspannin	20..253	CDD:395265	52/242 (21%)
		uroplakin_I_like_LEL	115..228	CDD:239409	19/121 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900