Protein Alignment lbm and TSPAN7

DIOPT Version :10

• Sequence 1: NP_523639.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 62/236 - (26%)
• Similarity: 102/236 - (43%)
• Gaps: 53/236 - (22%)

  Fly     3 CATTSVKIASIV--LNAVLGFLAAGAIG------WIAYNADTETEEFVIAAYIAC---SLILVFA 56
            |..|.:.|.|.|  :..|: .||.|..|      :|:..|:..|.    |.|:..   :.|:||.
Human    14 CLKTLLIIYSFVFWITGVI-LLAVGVWGKLTLGTYISLIAENSTN----APYVLIGTGTTIVVFG 73

  Fly    57 LLGIFAAIRESVVLTATSAVFLLILAILQIV---STCLFLHEFD---VKSGRDMVEVAWQANN-- 113
            |.|.||..|.|..:....|:||.::.:.::|   |..:|.||..   :::..|.:: .:..|:
Human    74 LFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQ-TYNGNDER 137

  Fly   114 ---MDSLQQKHECCGQSSAQDYIHLSLL-------IPPSCYADLQQT---PDHLY---------- 155
               :|.:|:...|||   .|:|.:.|..       |||||.  :.:|   |..|:
Human   138 SRAVDHVQRSLSCCG---VQNYTNWSTSPYFLEHGIPPSCC--MNETDCNPQDLHNLTVAATKVN 197

  Fly   156 LDGCIEKVQSFYESDKLRFIIVSWVLVAFELICFALAVFLA 196
            ..||.:.|.||.|::......|::.:...:||...||..|:
Human   198 QKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLS 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbm	NP_523639.1	Tetraspanin	<47..196	CDD:459767	46/182 (25%)
		tetraspanin_LEL	<109..169	CDD:239401	22/84 (26%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	61/235 (26%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	27/108 (25%)