Protein Alignment lbm and Tspan1

DIOPT Version :10

• Sequence 1: NP_523639.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: NP_598442.1
• Gene: Tspan1 / 66805
• MGIID: 1914055
• Length: 240
• Species: Mus musculus
• Alignment Length: 231
• Identity: 52/231 - (22%)
• Similarity: 96/231 - (41%)
• Gaps: 62/231 - (26%)

  Fly     5 TTSVKIASIVLNAVLGF-------LAAGAIGWI-----AYNADTETEEFVIAAYIACSLILVFAL 57
            |:.:|:...:.::.:.|       :||||:.:|     .|.|.:|.:         |.|::.|::
Mouse    37 TSFLKVFGSLSSSAMQFVNVGYFLIAAGAVLFILGFLGCYGAHSENK---------CVLMMFFSI 92

  Fly    58 LGI-----FAAIRESVVLTATSAVFLLILAILQIVSTCLFLHEFDVKSGRDMVEVAWQANNMDSL 117
            |.|     .|....::|.|..:..||.:|.:..|        |.|.....|..:| |..    ::
Mouse    93 LLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAI--------EKDYGYQTDFTQV-WNT----TM 144

  Fly   118 QQKHECCGQSSAQD-----YIHLSLLIPPSCYADLQQTPDHLYLDGCIE------KVQSFYESDK 171
            ::.| |||.::..|     ::..:.:.||.|.|:    |.:..::.|.|      |||..::...
Mouse   145 EELH-CCGFNNYTDFNASRFVKENKVFPPPCCAN----PGNHTVEPCTEEKAKSMKVQGCFKEIL 204

  Fly   172 LRF----IIVSWVLV---AFELICFALAVFLAISFK 200
            .|.    :.|..|.|   |.||....::::|..:.|
Mouse   205 HRIRANAVTVGGVAVGVAALELAAMVVSMYLYCNLK 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbm	NP_523639.1	Tetraspanin	<47..196	CDD:459767	39/171 (23%)
		tetraspanin_LEL	<109..169	CDD:239401	16/70 (23%)
Tspan1	NP_598442.1	Tetraspanin	7..>151	CDD:459767	30/136 (22%)
		uroplakin_I_like_LEL	106..208	CDD:239409	27/119 (23%)