DRSC/TRiP Functional Genomics Resources

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Protein Alignment lbm and Cd63

DIOPT Version :9

Sequence 1:NP_001260757.1 Gene:lbm / 35623 FlyBaseID:FBgn0016032 Length:208 Species:Drosophila melanogaster
Sequence 2:NP_001036045.1 Gene:Cd63 / 12512 MGIID:99529 Length:238 Species:Mus musculus


Alignment Length:227 Identity:51/227 - (22%)
Similarity:93/227 - (40%) Gaps:45/227 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 VKIASIVLNAVLGFLAAGAIGWIAYNADTE-------TEEFVIAAYIACSLILVFALL------G 59
            :|....:|..:|....|.|:|.||.....:       |.|....:.:...:|.|.|.|      |
Mouse     7 MKCVKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVG 71

  Fly    60 IFAAIRESVVLTATSAVFLLILAILQI-VSTCLFLHEFDVKSG---------RDMVEVAWQANNM 114
            ...|.:|:..|..|.|:||.::.:::: |:...::....|||.         ::.::....|..:
Mouse    72 CCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLKDNKTATIL 136

  Fly   115 DSLQQKHECCGQSSAQDYIHLSLL----IPPSCYA--------DLQQTPDHLYLDGCIEKVQSFY 167
            |.||:::.|||.|:..|:.::..:    :|.||..        |.:::..|  ..||:|.:..:.
Mouse   137 DKLQKENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFKESTIH--TQGCVETIAIWL 199

  Fly   168 ESDKLRFIIVSWVLVAFELICFALAVFLAISF 199
            ..:.|        |||...:..|....|.|.|
Mouse   200 RKNIL--------LVAAAALGIAFVEVLGIIF 223

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lbmNP_001260757.1 Tetraspannin 8..198 CDD:278750 49/224 (22%)
tetraspanin_LEL <109..169 CDD:239401 17/71 (24%)
Cd63NP_001036045.1 Tetraspannin 10..227 CDD:395265 50/224 (22%)
CD63_LEL 105..203 CDD:239419 20/99 (20%)
Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449 234..238
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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