Protein Alignment lbm and TSPAN1

DIOPT Version :10

• Sequence 1: NP_523639.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Alignment Length: 174
• Identity: 45/174 - (25%)
• Similarity: 67/174 - (38%)
• Gaps: 50/174 - (28%)

  Fly    10 IASIVLNAVLGFLAAGAIGWIAYNADTETEEFVIAAYIACSLI-LVFALLGIF----AAIRESVV 69
            ||:.|:...||||.       .|.|.||::         |:|: ..|.||.||    ||...::|
Human    61 IAAGVVVFALGFLG-------CYGAKTESK---------CALVTFFFILLLIFIAEVAAAVVALV 109

  Fly    70 LTATSAVFLLILAILQIVSTCLFLHEFDVKSGRDMVEVAWQANNMDSLQQKHECCGQSSAQD--- 131
            .|..:..||.:|.:..|        :.|..|..|..:| |. ..|..|    :|||.::..|
Human   110 YTTMAEHFLTLLVVPAI--------KKDYGSQEDFTQV-WN-TTMKGL----KCCGFTNYTDFED 160

  Fly   132 --YIHLSLLIPPSCYAD----------LQQTPDHLYLDGCIEKV 163
              |...:...||.|..|          .:|......::||..::
Human   161 SPYFKENSAFPPFCCNDNVTNTANETCTKQKAHDQKVEGCFNQL 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbm	NP_523639.1	Tetraspanin	<47..196	CDD:459767	34/137 (25%)
		tetraspanin_LEL	<109..169	CDD:239401	15/70 (21%)
TSPAN1	XP_011538762.1	Tetraspanin	7..>151	CDD:459767	34/119 (29%)
		uroplakin_I_like_LEL	110..212	CDD:239409	24/109 (22%)