Protein Alignment lbm and TSPAN5

DIOPT Version :10

• Sequence 1: NP_523639.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 45/229 - (19%)
• Similarity: 87/229 - (37%)
• Gaps: 66/229 - (28%)

  Fly    21 FLAAGAIGW----IAYNADTETE----EFVIAAYIACSLILVFALLGIFAAIRESVVLTATSAVF 77
            ||..|...|    :..|..:.|:    :.|....:...::.:....|...|:||:..|....:||
Human    33 FLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVF 97

  Fly    78 LLILAILQIVSTCL-------------FLHEFDVKSGRDMVEVAWQANNMDSLQQKHECCGQSSA 129
            |.|:..|::.:..|             |....::::.||.:::   .|.:|..|:..:|||...|
Human    98 LGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNIRAYRDDIDL---QNLIDFTQEYWQCCGAFGA 159

  Fly   130 QDYIHLSLL--------------IPPSCYA--------------DLQQTPD-----HLYLDGCIE 161
            .|: :|::.              :|.||..              |.:|.|:     .:|..||:.
Human   160 DDW-NLNIYFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVP 223

  Fly   162 KVQSFYESDKLRFIIVSWVLVAFEL-----ICFA 190
            :.:.:.:.:   ..||:.:.:...|     ||.|
Human   224 QFEKWLQDN---LTIVAGIFIGIALLQIFGICLA 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbm	NP_523639.1	Tetraspanin	<47..196	CDD:459767	38/195 (19%)
		tetraspanin_LEL	<109..169	CDD:239401	18/92 (20%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	45/229 (20%)
		TM4SF9_like_LEL	113..233	CDD:239412	21/126 (17%)