Protein Alignment Tsp42El and CD81

DIOPT Version :9

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_004347.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 236
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 65/236 - (27%)
• Similarity: 103/236 - (43%)
• Gaps: 47/236 - (19%)

  Fly     2 GCATGTIKYSLFLFN-ALW----AILGILV----------LIFGGLGWGAMPDAYAIGILIL--- 48
            || |..|||.||:|| ..|    .|||:.:          |::..||....|:.:.:||.||
Human     5 GC-TKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAV 68

  Fly    49 GGTILVISLFGCCGAVRESPRMLWTYASLLLILLLLIVAFIILN-------PKDV--FKKYALQT 104
            |..::.:...||.||::||..:|.|:.:.|:||....||..|..       .|||  |...|||.
Human    69 GAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQ 133

  Fly   105 VENQWELEQTKPGSMDIIQKTYY----CCGRDSAQDYLDIKFWNNTVPSSCCKDDSCVNPLNLYV 165
            .....:....|     .:.||::    |||..:..........||..||.    .:.::  ||:.
Human   134 AVVDDDANNAK-----AVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSG----SNIIS--NLFK 187

  Fly   166 RGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILAI 206
            ..|..|:::.|:.:...:|.....:    |||::..:||::
Human   188 EDCHQKIDDLFSGKLYLIGIAAIVV----AVIMIFEMILSM 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspannin	7..196	CDD:278750	57/219 (26%)
		tetraspanin_LEL	94..178	CDD:239401	22/89 (25%)
CD81	NP_004347.1	Tetraspannin	10..226	CDD:395265	62/230 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910