Protein Alignment Tsp42El and TSPAN18

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 62/259 - (23%)
• Similarity: 102/259 - (39%)
• Gaps: 74/259 - (28%)

  Fly     2 GCATGTIKYSLFLFNALWAILGILVLIFGGLGW------------GAMP----DAYAIGILILGG 50
            |.....:||.:|:|| .:..||...|:..|: |            .|.|    .||.  :|.:||
Human    13 GDCLSCMKYLMFVFN-FFIFLGGACLLAIGI-WVMVDPTGFREIVAANPLLLTGAYI--LLAMGG 73

  Fly    51 TILVISLFGCCGAVRESPRMLWTYASLLLILLL-----LIVAFIILN--PKDVFKKYALQTVENQ 108
            .:.::...||||||||:..:|..:...:||:.|     .|:|||...  .::.|.|
Human    74 LLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTK--------- 129

  Fly   109 WELEQTKPGSMDI---------IQKTYYCCGRDSAQDY----------LDIKFWNNTVPSSCCK- 153
             ||.:...|:.|.         :..|:.|||.:..:|:          ||    :..||.:||:
Human   130 -ELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLD----SEEVPEACCRR 189

  Fly   154 -----------DDSCVNPLNLYV--RGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIIL 204
                       .:.|:...:|::  :||...:...|.......|.|..|:|......::.|:.|
Human   190 EPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCL 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	41/153 (27%)
		tetraspanin_LEL	94..178	CDD:239401	22/116 (19%)
TSPAN18	XP_005253274.1	Tetraspanin	20..255	CDD:459767	61/252 (24%)
		uroplakin_I_like_LEL	115..228	CDD:239409	25/126 (20%)