Protein Alignment Tsp42El and TSPAN4

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_001426622.1
• Gene: TSPAN4 / 7106
• HGNCID: 11859
• Length: 330
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 63/229 - (27%)
• Similarity: 105/229 - (45%)
• Gaps: 43/229 - (18%)

  Fly     8 IKYSLFLFNALWAILGILVLIFGGLG-W------------GAMPDAYAIGILIL-GGTILVISLF 58
            :||.:|.||.|:.:.|..||   |:| |            .:.|...|..:||: |..::.|...
Human   101 VKYLMFAFNLLFWLGGCGVL---GVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGFV 162

  Fly    59 GCCGAVRESPRMLWTYASLLLILLLL--IVAFIILNPKDVFKKYALQTVENQWELEQTK-----P 116
            ||.||::|:..:|.|:..|||::.||  .:|.:.....|...:||.|.::....|..|:     .
Human   163 GCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQGNVGLT 227

  Fly   117 GSMDIIQKTYYCCGRDSAQDYLDIKFWNNT-VPSSCCKD--DSCVNPLNLYVRG------CLIKV 172
            .:..|||..:.|||..:..|:.::  :|.| ||.|||.:  :||    .|:..|      |...|
Human   228 NAWSIIQTDFRCCGVSNYTDWFEV--YNATRVPDSCCLEFSESC----GLHAPGTWWKAPCYETV 286

  Fly   173 EEAFADEATTLGYLEWGLLGFNAVILLLAIILAI 206
            :....:....:|.  :||.  .|::.:|.:..|:
Human   287 KVWLQENLLAVGI--FGLC--TALVQILGLTFAM 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	41/142 (29%)
		tetraspanin_LEL	94..178	CDD:239401	26/97 (27%)
TSPAN4	NP_001426622.1	None