Protein Alignment Tsp42El and TSPAN7

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 61/236 - (25%)
• Similarity: 104/236 - (44%)
• Gaps: 50/236 - (21%)

  Fly     8 IKYSLFLFNALWAILGILVLIFGGLGWGAMPDAYAIGILI------------LGGTILVISLFGC 60
            :|..|.:::.::.|.|:::|..|  .||.:.....|.::.            .|.||:|..||||
Human    15 LKTLLIIYSFVFWITGVILLAVG--VWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGC 77

  Fly    61 CGAVRESPRMLWTYASLL-LILLLLIVA----FIILNP-KDVF-KKY--ALQTVENQWELEQTKP 116
            ....|.||.||..||..| |:.|..:||    |:..:. ||.| :.|  |:||.....|    :.
Human    78 FATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNGNDE----RS 138

  Fly   117 GSMDIIQKTYYCCGRDSAQDYLDIKFWNNT-------VPSSCCKDDSCVNPLNLY---------- 164
            .::|.:|::..|||   .|:|.:   |:.:       :|.|||.:::..||.:|:
Human   139 RAVDHVQRSLSCCG---VQNYTN---WSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVN 197

  Fly   165 VRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILA 205
            .:||...|..........:..:.:|:.....:.:|||..|:
Human   198 QKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLS 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	41/142 (29%)
		tetraspanin_LEL	94..178	CDD:239401	26/103 (25%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	61/236 (26%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	27/112 (24%)