Protein Alignment Tsp42El and Tspan15

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_001108504.1
• Gene: Tspan15 / 679462
• RGDID: 1588304
• Length: 294
• Species: Rattus norvegicus
• Alignment Length: 254
• Identity: 64/254 - (25%)
• Similarity: 111/254 - (43%)
• Gaps: 63/254 - (24%)

  Fly     7 TIKYSLFLFNALWAILGILVLIFGGLG------WGAMPDAY---AIGILILGGTILVISLFGCCG 62
            ::|:||.:::.::.::|.|||..|...      :..:..|:   ||.:::||..:.::|..|...
  Rat    19 SLKFSLIIYSTVFWLIGGLVLSVGIYAEAERQKYKTLESAFLAPAIILILLGVVMFIVSFIGVLA 83

  Fly    63 AVRESPRMLWTYASLLLILLLL-----IVAFIILNPK-DVFKKYALQTVENQWELEQTKPGSMDI 121
            ::|::..:|.::..:|.:.|::     |||.|..|.. |.......:.:||.::....| ..||.
  Rat    84 SLRDNLCLLQSFMFILGLCLVMELIGGIVALIFRNQTIDFLNDNIRRGIENYYDDLDFK-NIMDF 147

  Fly   122 IQKTYYCCGRDSAQDYLDIKFWNNT--------------VPSSCC----------------KDDS 156
            :||.:.|||   .:||.|   |:..              ||.:||                .|..
  Rat   148 VQKKFKCCG---GEDYRD---WSKNQYHDCSAPGPLACGVPYTCCIRNTTDVVNTMCGYKTIDKE 206

  Fly   157 CVNPLN-LYVRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILL---LAIILAIHYTNR 211
            .:|..| ::||||...|...|.|..:.:..|   |||    |||   |.::|.:.|..|
  Rat   207 RLNAQNIIHVRGCTNAVLIWFMDNYSIMAGL---LLG----ILLPQFLGVLLTLLYITR 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	33/136 (24%)
		tetraspanin_LEL	94..178	CDD:239401	28/115 (24%)
Tspan15	NP_001108504.1	Tetraspanin	20..>157	CDD:459767	35/140 (25%)
		penumbra_like_LEL	114..231	CDD:239411	31/123 (25%)