Protein Alignment Tsp42El and Tspan1

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_598442.1
• Gene: Tspan1 / 66805
• MGIID: 1914055
• Length: 240
• Species: Mus musculus
• Alignment Length: 246
• Identity: 60/246 - (24%)
• Similarity: 100/246 - (40%)
• Gaps: 57/246 - (23%)

  Fly     8 IKYSLFLFNALWAILGILVL---------------IFGGLGWGAMPDAYAIGILILGGTIL-VIS 56
            ||..:||||.|..:.|..:|               :||.|...||........||..|.:| ::.
Mouse     7 IKVMMFLFNLLIFLCGAALLAVGIWVSVDGTSFLKVFGSLSSSAMQFVNVGYFLIAAGAVLFILG 71

  Fly    57 LFGCCGAVRESPRMLWTYASLLLILLL-----LIVAFIILNPKDVF----------KKYALQTVE 106
            ..||.||..|:..:|..:.|:|||:.:     .:||.:.....:.|          |.|..||..
Mouse    72 FLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVPAIEKDYGYQTDF 136

  Fly   107 NQ-WELEQTKPGSMDIIQKTYYCCGRDSAQDYLDIKF--WNNTVPSSCCKD--DSCVNPL----- 161
            .| |          :...:..:|||.::..|:...:|  .|...|..||.:  :..|.|.
Mouse   137 TQVW----------NTTMEELHCCGFNNYTDFNASRFVKENKVFPPPCCANPGNHTVEPCTEEKA 191

  Fly   162 -NLYVRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILAIH-YTN 210
             ::.|:||..::.......|.|:|.:..|:    |.:.|.|:::::: |.|
Mouse   192 KSMKVQGCFKEILHRIRANAVTVGGVAVGV----AALELAAMVVSMYLYCN 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	38/153 (25%)
		tetraspanin_LEL	94..178	CDD:239401	21/104 (20%)
Tspan1	NP_598442.1	Tetraspanin	7..>151	CDD:459767	38/153 (25%)
		uroplakin_I_like_LEL	106..208	CDD:239409	23/111 (21%)