Protein Alignment Tsp42El and Tspan6

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_062630.2
• Gene: Tspan6 / 56496
• MGIID: 1926264
• Length: 245
• Species: Mus musculus
• Alignment Length: 230
• Identity: 58/230 - (25%)
• Similarity: 103/230 - (44%)
• Gaps: 30/230 - (13%)

  Fly     8 IKYSLFLFNALWAILGILVLIFGGLGWGAMPDAYAI---------GILILGGTILV-ISLFGCCG 62
            :|..|.::..::.|.|:::|..|..|..::.:.:::         .:||..||::: :..|||..
Mouse    17 LKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIGTGTVIILLGTFGCFA 81

  Fly    63 AVRESPRMLWTYASLLLILLLL-----IVAFIILNP-KDVFKKYALQTVENQWELEQTKPGSMDI 121
            ..|.|..||..||..|.::.|:     ||.|:..:. |:.||......::........:..::|.
Mouse    82 TCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTGDYRSEAVDK 146

  Fly   122 IQKTYYCCGRDSAQDYLDIKFWNNT-VPSSCCKDDSC--------VNPLNLYVRGCLIKVEEAFA 177
            ||.|.:|||..:..|:....:::.| .|.||||.:.|        ||.     .||.|||.....
Mouse   147 IQSTLHCCGVTNYGDWKGTNYYSETGFPKSCCKLEGCYPQRDADKVNE-----EGCFIKVMTTIE 206

  Fly   178 DEATTLGYLEWGLLGFNAVILLLAIILAIHYTNRR 212
            .|...:..:.:|:..|..:.:.||..|:...||.:
Mouse   207 SEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	33/137 (24%)
		tetraspanin_LEL	94..178	CDD:239401	25/92 (27%)
Tspan6	NP_062630.2	Tetraspanin	17..235	CDD:459767	56/222 (25%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	26/101 (26%)