Protein Alignment Tsp42El and Tspan3

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_062767.3
• Gene: Tspan3 / 56434
• MGIID: 1928098
• Length: 253
• Species: Mus musculus
• Alignment Length: 260
• Identity: 71/260 - (27%)
• Similarity: 113/260 - (43%)
• Gaps: 67/260 - (25%)

  Fly     1 MG-CATGTIKYSLFLFNAL-WAILGILVLIFGGLGWGA------------MPDAY----AIGILI 47
            || |...:.|..|...|.: |...|||..:      ||            ..|.|    |:.|:.
Mouse     1 MGQCGITSSKTVLVFLNLIFWGAAGILCYV------GAYVFITYDDYDHFFEDVYTLFPAVVIIA 59

  Fly    48 LGGTILVISLFGCCGAVRESPRMLWTYASLLLILLLLIVAFIILNPKDVFKKYALQT-VENQ--- 108
            :|..:.:|.|.|||..:|||...|.|:..:||::.:..|..::|.       |..:. |||:
Mouse    60 VGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLG-------YVYRAKVENEVDR 117

  Fly   109 --WELEQTKPG--------SMDIIQKTYYCCGRDSAQDYLDIKFW----NNTVPSSCCKD--DSC 157
              .::.:|..|        ::|.:|:..:|||..:..|:.:..::    |.:||.|||::  .||
Mouse   118 SIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAKSC 182

  Fly   158 ----VNPLNLYVRGC----LIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILAIHYTNRRRR 214
                .||.:||..||    :.|::|       .|.::.|..|.| |.|.||.::.|.....||.|
Mouse   183 NGSLANPSDLYAEGCEALVVKKLQE-------ILMHVIWAALAF-AAIQLLGMLCACIVLCRRSR 239

  Fly   215  214
            Mouse   240  239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	37/152 (24%)
		tetraspanin_LEL	94..178	CDD:239401	28/111 (25%)
Tspan3	NP_062767.3	Tetraspanin	9..235	CDD:459767	65/246 (26%)
		TM4SF8_like_LEL	104..210	CDD:239416	28/119 (24%)