Protein Alignment Tsp42El and tspan5b

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_001008591.1
• Gene: tspan5b / 494048
• ZFINID: ZDB-GENE-041212-12
• Length: 271
• Species: Danio rerio
• Alignment Length: 256
• Identity: 60/256 - (23%)
• Similarity: 111/256 - (43%)
• Gaps: 63/256 - (24%)

  Fly     1 MGCATGTIKYSLFLFNALWAILGILVLIFGGLGW---GAMPDAYAIG----------ILILGGTI 52
            :||.   |||.:|.||.::.:||:..|......|   |.:.:..:|.          .|::||.:
Zfish    11 VGCC---IKYFIFGFNIIFWLLGVAFLSVALWAWSEKGVLSNISSITDLGGFDPVWLFLVVGGVM 72

  Fly    53 LVISLFGCCGAVRESPRMLWTYASLLLILLLL-----IVAFIILN-PKDVFKKYA---LQTVENQ 108
            .|:...||.||:||:..:|..::..|.|:..|     ::||:..: .||..|.:.   ::...:.
Zfish    73 FVLGFAGCIGALRENSFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLKFFINNNIRAYRDD 137

  Fly   109 WELEQTKPGSMDIIQKTYYCCGRDSAQDY-LDIKFWNNT----------VPSSCCKDDSCVNPLN 162
            .:|:..    :|..|..:.|||....:|: |:| ::|.|          ||.|||..|...:.:|
Zfish   138 IDLQNL----IDFTQDYWECCGAFGPEDWNLNI-YFNCTDTNLSREKCGVPFSCCTKDPAEDVIN 197

  Fly   163 ------------------LYVRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILA 205
                              ::.:||:.:.|:...:..|.:..:..|:    |::.:..|.||
Zfish   198 TQCGYDIRGKGDIEHKTFIHTKGCVPQFEKWLQENLTVVAGIFIGI----ALLQIFGICLA 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	35/143 (24%)
		tetraspanin_LEL	94..178	CDD:239401	24/115 (21%)
tspan5b	NP_001008591.1	Tetraspanin	15..258	CDD:459767	58/249 (23%)
		TM4SF9_like_LEL	113..233	CDD:239412	25/124 (20%)