Protein Alignment Tsp42El and TSPAN33

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 58/245 - (23%)
• Similarity: 103/245 - (42%)
• Gaps: 56/245 - (22%)

  Fly     8 IKYSLFLFNAL-WAILGILVLIFGGLGWGAMPDAY----------AIGILILGGTILVISLFGCC 61
            :||.||.||.| |.|..::|.:  |:....|..|.          ||.::::|..:.:::..||.
Human    22 VKYLLFFFNMLFWVISMVMVAV--GVYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGCI 84

  Fly    62 GAVRESPRMLWTYASLLLILLLL-----IVAFIILNPKDVFKKYALQTVEN---QWELEQTKPGS 118
            |::||:..:|.|::..|..:.||     |:.|:.   .|..:....:.:.|   .:..:......
Human    85 GSLRENICLLQTFSLCLTAVFLLQLAAGILGFVF---SDKARGKVSEIINNAIVHYRDDLDLQNL 146

  Fly   119 MDIIQKTYYCCGRDSAQDYLDIKFWN----------NTVPSSCC---KDDSCVNPL--------- 161
            :|..||.:.|||..|.:|:....::|          .:||.|||   .|.:.:|.:
Human   147 IDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINTMCGQGMQAFD 211

  Fly   162 ------NLYVRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILA 205
                  .:|..||:.|:..........||.:..||    |:..|:.|:|:
Human   212 YLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGL----AIPQLVGILLS 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	34/140 (24%)
		tetraspanin_LEL	94..178	CDD:239401	22/114 (19%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	58/245 (24%)
		penumbra_like_LEL	116..236	CDD:239411	23/122 (19%)