Protein Alignment Tsp42El and Tspan12

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_766595.1
• Gene: Tspan12 / 269831
• MGIID: 1889818
• Length: 305
• Species: Mus musculus
• Alignment Length: 256
• Identity: 54/256 - (21%)
• Similarity: 95/256 - (37%)
• Gaps: 72/256 - (28%)

  Fly    12 LFLFNALWAILGILVLIFGGLGWGAMPDAYAIGILILGGT------------------------- 51
            |:..|.|:.::.|.||...  .|  |.| |...:|.|...
Mouse    14 LYALNLLFWLMSISVLAVS--AW--MRD-YLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCF 73

  Fly    52 ILVISLFGCCGAVRESPRML-WTYASLLLILLLLIVAFIILNPKDVFKKYALQTVENQW------ 109
            ::::.:.|.||.|:.:..:| |.:.:||:|..:.:...:....::|.       |..||
Mouse    74 LIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVM-------VPVQWSDMVTL 131

  Fly   110 ELEQTKPG---------SMDIIQKTYYCCGRDSAQDYLDI--KFWNNTVPSSCCKDD--SCVNPL 161
            :...|..|         :.:..|:.:.|||.....|:|::  ..|   .|.|||..:  .|....
Mouse   132 KARMTNYGLPRYRWLTHAWNYFQREFKCCGVVYFTDWLEMTEMDW---PPDSCCVREFPGCSKQA 193

  Fly   162 ------NLYVRGCLIKVEEAFADEATTLGYLEW-----GLLGFNAVILLLAIILAIHYTNR 211
                  :||..||..|: .:|......|..|.:     |:....|:||.:.::.|::|..|
Mouse   194 HQEDLSDLYQEGCGKKM-YSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLWALYYDRR 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	29/158 (18%)
		tetraspanin_LEL	94..178	CDD:239401	24/108 (22%)
Tspan12	NP_766595.1	Tetraspanin	10..246	CDD:459767	51/247 (21%)
		TM4SF12_like_LEL	116..218	CDD:239410	24/112 (21%)