Protein Alignment Tsp42El and Tspan7

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_062608.2
• Gene: Tspan7 / 21912
• MGIID: 1298407
• Length: 249
• Species: Mus musculus
• Alignment Length: 233
• Identity: 58/233 - (24%)
• Similarity: 104/233 - (44%)
• Gaps: 44/233 - (18%)

  Fly     8 IKYSLFLFNALWAILGILVLIFGGLGWGAMPDAYAIGILI------------LGGTILVISLFGC 60
            :|..|.:::.::.|.|:::|..|  .||.:.....|.::.            .|.||:|..||||
Mouse    15 LKTLLIIYSFVFWITGVILLAVG--VWGKLTLGTYISLIAENSTNAPYVLIGTGTTIVVFGLFGC 77

  Fly    61 CGAVRESPRMLWTYASLL-LILLLLIVA----FIILNP-KDVFKKYALQTVENQWELEQTKPGSM 119
            ....|.||.||..||..| |:.|..:||    |:..:. ||.|.:.....::| :.....:..::
Mouse    78 FATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQN-YNGNDERSRAV 141

  Fly   120 DIIQKTYYCCGRDSAQDYLDIKFWNNT-------VPSSCCKDDSCVNPLNLY----------VRG 167
            |.:|::..|||   .|:|.:   |:::       :|.|||.:::..|||:|:          .:|
Mouse   142 DHVQRSLSCCG---VQNYTN---WSSSPYFLDHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKG 200

  Fly   168 CLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILA 205
            |...|..........:..:.:|:.....:.:|||..|:
Mouse   201 CYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLS 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	37/139 (27%)
		tetraspanin_LEL	94..178	CDD:239401	23/100 (23%)
Tspan7	NP_062608.2	Tetraspanin	15..239	CDD:459767	58/233 (25%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	24/109 (22%)