Protein Alignment Tsp42El and tsp-14

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_001367834.1
• Gene: tsp-14 / 180761
• WormBaseID: WBGene00006640
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 279
• Identity: 63/279 - (22%)
• Similarity: 103/279 - (36%)
• Gaps: 100/279 - (35%)

  Fly     8 IKYSLFLFNALWAILGILVLIFGGLGWGAMPDAY------------------AIGILILGGTILV 54
            :|:.:||.|::..::|:.:|..|         .|                  ||.|.|.|.:|.|
 Worm    54 LKWLVFLLNSIVFLVGVGILALG---------VYLFIKDFREVKLVDIILNPAILISIFGFSICV 109

  Fly    55 ISLFGCCGAVRESPRMLWTYASLLLILLLLIVAFIILNPKDVFKKYALQTVEN---QWEL----- 111
            :|.||..||:|::..:|..:|:.:.:..:|:||..::    .|..:...|.|.   .|.|
 Worm   110 VSFFGFMGALRDNIFLLKCFAACVFLSYILVVAVTLV----FFTLFYTDTTEGLSANWLLLYAVK 170

  Fly   112 ----EQTKPGSMDIIQKTYYCCGRDS-AQDYLDIKFWNNT----------------VPSSCCKDD 155
                .:.....||.:|:...|||..| ||.|.|   ||.:                ||.|||:..
 Worm   171 NYHTNRNLAEIMDALQENLECCGVSSIAQGYRD---WNMSYQFNCTNSNPQPEKCGVPFSCCRKS 232

  Fly   156 ------SCVNPL-----------------------NLYVRGCLIKVEEAFADEATTLGYLEWGLL 191
                  ...|||                       ::|.||||..:...|...|..:|..
 Worm   233 VISEAAGSSNPLLPAMRSLECWQNALTKRPGDLEHDIYTRGCLQPLRTLFESHAVHVGAF----- 292

  Fly   192 GFNAVILLLAIILAIHYTN 210
               ..:|::.:.:::..||
 Worm   293 ---VALLIVPVCISVCLTN 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	35/151 (23%)
		tetraspanin_LEL	94..178	CDD:239401	32/141 (23%)
tsp-14	NP_001367834.1	Tetraspanin	54..>193	CDD:459767	35/151 (23%)
		tetraspanin_LEL	145..286	CDD:351888	32/147 (22%)