Protein Alignment Tsp42El and Tspan8

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_598210.1
• Gene: Tspan8 / 171048
• RGDID: 621783
• Length: 235
• Species: Rattus norvegicus
• Alignment Length: 242
• Identity: 74/242 - (30%)
• Similarity: 107/242 - (44%)
• Gaps: 52/242 - (21%)

  Fly     1 MGCATGTIKYSLFLFNALWAILGILVLIFGGLG-W----------------GAMPDAYAIGILI- 47
            |...:|.:|||:|.||.|:.:.|.|:|   ||. |                |..| ..|:.|||
  Rat     1 MAGVSGCLKYSMFFFNFLFWVCGTLIL---GLAIWLRVSKDGKEIITSGDNGTNP-FIAVNILIA 61

  Fly    48 LGGTILVISLFGCCGAVRESPRMLWTYASLLLILLLLIVAFIILNPKDVFKKYALQTV-----EN 107
            :|..|:|:...||||||:||..||..:...||::|||.||..||..  .||..:.:.:     ||
  Rat    62 VGSIIMVLGFLGCCGAVKESRCMLLLFFIGLLLILLLQVAAGILGA--TFKSESSRILNETLYEN 124

  Fly   108 QWELEQTKPGSMDI------IQKTYYCCG-RDSAQDYLDIKFWNNTVP---SSC-CKDDSC--VN 159
            ...|.:|...:.::      .|..:.||| |..|.|      |....|   .|| |....|  .|
  Rat   125 AKLLSETSNEAKEVQKAMIAFQSEFKCCGLRFGAAD------WGKNFPDAKESCQCTGSDCESYN 183

  Fly   160 PLNLYVRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILAI 206
            ..|:|...||..::|........:..:.:||    |||.:|.::.::
  Rat   184 GENVYRTTCLSLIKELVEKNIIIVIGIAFGL----AVIEILGLVFSM 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	49/150 (33%)
		tetraspanin_LEL	94..178	CDD:239401	25/101 (25%)
Tspan8	NP_598210.1	Tetraspanin	8..230	CDD:459767	72/235 (31%)
		TM4SF3_like_LEL	106..204	CDD:239407	25/105 (24%)