DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42El and Cd63

DIOPT Version :9

Sequence 1:NP_523638.1 Gene:Tsp42El / 35622 FlyBaseID:FBgn0033134 Length:217 Species:Drosophila melanogaster
Sequence 2:NP_001036045.1 Gene:Cd63 / 12512 MGIID:99529 Length:238 Species:Mus musculus


Alignment Length:245 Identity:59/245 - (24%)
Similarity:102/245 - (41%) Gaps:78/245 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 CATGTIKYSLFLFNALWAILGILVLIF-----------GGLGWGAMPDAYAIGILILGGTILVIS 56
            ||.|.|            .:|:.|.:.           |.|    :|    :.|:.:|..:.:::
Mouse    24 CAVGLI------------AIGVAVQVVLKQAITHETTAGSL----LP----VVIIAVGAFLFLVA 68

  Fly    57 LFGCCGAVRESPRMLWTYASLLLILLLLIVAFIIL------NPKDVFKKYALQTVENQWELEQTK 115
            ..|||||.:|:..::.|:|..|.:::|:.||..|.      ..|..|.|...|.::|.  |:..|
Mouse    69 FVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNY--LKDNK 131

  Fly   116 PGS-MDIIQKTYYCCGRDSAQDYLDIKFWNN-------TVPSSCC-----------KDDS----- 156
            ..: :|.:||...|||   |.:|.|   |.|       .||.|||           |:.:     
Mouse   132 TATILDKLQKENNCCG---ASNYTD---WENIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQG 190

  Fly   157 CVNPLNLYVRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILAI 206
            ||..:.:::|..::.|..|    |..:.::|  :||   :|....::.:|
Mouse   191 CVETIAIWLRKNILLVAAA----ALGIAFVE--VLG---IIFSCCLVKSI 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42ElNP_523638.1 Tetraspannin 7..196 CDD:278750 54/229 (24%)
tetraspanin_LEL 94..178 CDD:239401 29/107 (27%)
Cd63NP_001036045.1 Tetraspannin 10..227 CDD:395265 58/239 (24%)
CD63_LEL 105..203 CDD:239419 27/105 (26%)
Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449 234..238
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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