Protein Alignment Tsp42El and Cd151

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_033972.2
• Gene: Cd151 / 12476
• MGIID: 1096360
• Length: 253
• Species: Mus musculus
• Alignment Length: 226
• Identity: 58/226 - (25%)
• Similarity: 98/226 - (43%)
• Gaps: 44/226 - (19%)

  Fly     3 CATGTIKYSLFLFNALWAILGILVLIFGGLGWGAMPD-----------AYAIGILILGGTILVIS 56
            |.|..:||.||.:|..:.:.|:.|:..|........|           |.|..:::.|..::|..
Mouse    11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASSTYLATAYILVVAGVVVMVTG 75

  Fly    57 LFGCCGAVRESPRMLWTYASLLLILLLL-IVAFIILNPKDVFKKYALQTVENQWELEQTK----- 115
            :.|||...:|...:|..|..||||:.|| |:|.|:     .:..|.....|.:..|:.|.
Mouse    76 VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGIL-----AYVYYQQLNTELKENLKDTMVKRYH 135

  Fly   116 -------PGSMDIIQKTYYCCGRDSAQDYLDIKFW-------NNTVPSSCCKD--DSC---VNPL 161
                   ..::|.:|:.::|||.:::||:.|.: |       :..||.||||.  ..|   .:..
Mouse   136 QSGHEGVSSAVDKLQQEFHCCGSNNSQDWQDSE-WIRSGEADSRVVPDSCCKTMVAGCGKRDHAS 199

  Fly   162 NLY--VRGCLIKVEEAFADEATTLGYLEWGL 190
            |:|  ..||:.|:|....:....:|.:..|:
Mouse   200 NIYKVEGGCITKLETFIQEHLRVIGAVGIGI 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	35/145 (24%)
		tetraspanin_LEL	94..178	CDD:239401	26/109 (24%)
Cd151	NP_033972.2	Tetraspanin	16..246	CDD:459767	56/221 (25%)
		CD151_like_LEL	112..220	CDD:239408	26/108 (24%)