DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42El and TSPAN3

DIOPT Version :9

Sequence 1:NP_523638.1 Gene:Tsp42El / 35622 FlyBaseID:FBgn0033134 Length:217 Species:Drosophila melanogaster
Sequence 2:NP_005715.1 Gene:TSPAN3 / 10099 HGNCID:17752 Length:253 Species:Homo sapiens


Alignment Length:264 Identity:69/264 - (26%)
Similarity:109/264 - (41%) Gaps:75/264 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MG-CATGTIKYSLFLFNAL-WAILGILVLIFGGLGWGA------------MPDAY----AIGILI 47
            || |...:.|..|...|.: |...|||..:      ||            ..|.|    |:.|:.
Human     1 MGQCGITSSKTVLVFLNLIFWGAAGILCYV------GAYVFITYDDYDHFFEDVYTLIPAVVIIA 59

  Fly    48 LGGTILVISLFGCCGAVRESPRMLWTYASLLLILLLLIVAFIIL---------NPKD-----VFK 98
            :|..:.:|.|.|||..:|||...|.|:..:||::.:..|..::|         |..|     |:|
Human    60 VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYK 124

  Fly    99 KYALQTVENQWELEQTKPG----SMDIIQKTYYCCGRDSAQDYLDIKFW----NNTVPSSCCKD- 154
            .|           ..|.|.    ::|.:|:..:|||..:..|:.:..::    |.:||.|||:: 
Human   125 TY-----------NGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRET 178

  Fly   155 -----DSCVNPLNLYVRGC----LIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILAIHYTN 210
                 .|..:|.:||..||    :.|::|       .:.::.|..|.| |.|.||.::.|.....
Human   179 ASNCNGSLAHPSDLYAEGCEALVVKKLQE-------IMMHVIWAALAF-AAIQLLGMLCACIVLC 235

  Fly   211 RRRR 214
            ||.|
Human   236 RRSR 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42ElNP_523638.1 Tetraspannin 7..196 CDD:278750 58/237 (24%)
tetraspanin_LEL 94..178 CDD:239401 26/106 (25%)
TSPAN3NP_005715.1 Tetraspannin 9..232 CDD:395265 63/247 (26%)
TM4SF8_like_LEL 104..210 CDD:239416 27/123 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1406905at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19282
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.920

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