Protein Alignment Tsp42El and TSPAN5

DIOPT Version :10

• Sequence 1: NP_523638.1
• Gene: Tsp42El / 35622
• FlyBaseID: FBgn0033134
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 62/248 - (25%)
• Similarity: 105/248 - (42%)
• Gaps: 58/248 - (23%)

  Fly     8 IKYSLFLFNALWAILGILVLIFGGLGW---GAMPDAYAIG----------ILILGGTILVISLFG 59
            |||.:|.||.::..|||..|..|...|   |.:.:..:|.          .|::||.:.::...|
Human    15 IKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAG 79

  Fly    60 CCGAVRESPRMLWTYASLLLILLLL-----IVAFIILNPKDVFKKYALQTVENQ---WELEQTKP 116
            |.||:||:..:|..::..|.|:..|     ::||:.   ||..|......:.|.   :..:....
Human    80 CIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVF---KDWIKDQLYFFINNNIRAYRDDIDLQ 141

  Fly   117 GSMDIIQKTYYCCGRDSAQDY-LDIKFWNNT----------VPSSCCKDDSCVNPLN-------- 162
            ..:|..|:.:.|||...|.|: |:| ::|.|          ||.|||..|...:.:|
Human   142 NLIDFTQEYWQCCGAFGADDWNLNI-YFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDAR 205

  Fly   163 ----------LYVRGCLIKVEEAFADEATTLGYLEWGLLGFNAVILLLAIILA 205
                      :|.:||:.:.|:...|..|.:..:..|:    |::.:..|.||
Human   206 QKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGI----ALLQIFGICLA 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42El	NP_523638.1	Tetraspanin	8..>130	CDD:459767	36/142 (25%)
		tetraspanin_LEL	94..178	CDD:239401	26/115 (23%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	62/248 (25%)
		TM4SF9_like_LEL	113..233	CDD:239412	28/123 (23%)