DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ej and CD63

DIOPT Version :9

Sequence 1:NP_523636.1 Gene:Tsp42Ej / 35620 FlyBaseID:FBgn0033132 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_001244318.1 Gene:CD63 / 967 HGNCID:1692 Length:238 Species:Homo sapiens


Alignment Length:236 Identity:57/236 - (24%)
Similarity:89/236 - (37%) Gaps:52/236 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 KYGLLVTCILIVTCNVFFFSCGV-------------TTWGS-------AVSVYGSYGSALCGGAV 55
            |:.|.|..:....|.|...:.||             .|.||       ||.|:           :
Human    11 KFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVF-----------L 64

  Fly    56 FGVAFLGMYVALKVSYKYSIYYLICSGLVI-----AALGSYLFTFTAMREQLMGRFEERMRDLFE 115
            |.|||:|...|.|.:|...|.:.|...|::     ||:..|:|     |:::|..|....|...|
Human    65 FLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVF-----RDKVMSEFNNNFRQQME 124

  Fly   116 ---RKTHSDDKMQPVHSLFGCCGIEGPQDYLQ---EEHGALPSSCC--YAFDCS---KPAHVYEE 169
               :..|:...:..:.:.|.|||.....|:.:   .....:|.|||  ....|.   ....:::|
Human   125 NYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKE 189

  Fly   170 GCSTKAVATLRMQAELNYYSCMAIIALEFLGLFTAYHLGKA 210
            ||..|....||....:...:.:.|..:|.||:..|..|.|:
Human   190 GCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKS 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EjNP_523636.1 Tetraspannin 11..211 CDD:278750 57/236 (24%)
tetraspanin_LEL 97..183 CDD:239401 22/96 (23%)
CD63NP_001244318.1 Tetraspannin 10..227 CDD:395265 55/231 (24%)
CD63_LEL 105..203 CDD:239419 24/102 (24%)
Lysosomal targeting motif. /evidence=ECO:0000250|UniProtKB:P41731 234..238
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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