Protein Alignment Tsp42Ej and tspan8

DIOPT Version :10

• Sequence 1: NP_523636.1
• Gene: Tsp42Ej / 35620
• FlyBaseID: FBgn0033132
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_001011430.2
• Gene: tspan8 / 496915
• XenbaseID: XB-GENE-1016291
• Length: 230
• Species: Xenopus tropicalis
• Alignment Length: 219
• Identity: 42/219 - (19%)
• Similarity: 70/219 - (31%)
• Gaps: 90/219 - (41%)

  Fly    25 NVFFFSC-----GVTTW----------------------------GSAVSVYGSYGSALCGGAV- 55
            |..|:.|     ||:.|                            |:.:.|.|.:|   |.||:
 Frog    16 NFLFWLCGCVILGVSIWVRVSKSVQQELNIDGGSLLSAVDLMIAVGAIIMVLGFFG---CCGAIR 77

  Fly    56 -----FGVAFLGMYVALKVSYKYSIYYLICSGLVIAALGSYLFTFTAMREQLMGRFEERMRDLFE 115
                 ..:.|:|:::.|.:.....:...:....:.|.|....:....:..|     :|..:..||
 Frog    78 ESRCLLLLFFIGLFLILALQITAGVLGAVYKPKIEAQLNQTFYKLLPLSGQ-----DESFKTSFE 137

  Fly   116 RKTHSDDKMQPVHSLFGCCG-IEGPQDYLQEEHGA-LPSSCCYAFDCSKPAHVYEEGCSTKAVAT 178
            .          :.....||| :.|..|:     || :|:||.               |.|    |
 Frog   138 N----------IQKESQCCGLVNGYTDW-----GANVPASCI---------------CPT----T 168

  Fly   179 LRMQ-----AELNYY--SCMAIIA 195
            .|..     |..|||  :|:.:|:
 Frog   169 SRTNNCIYFAGKNYYKETCLGVIS 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ej	NP_523636.1	Tetraspanin	11..>135	CDD:459767	23/148 (16%)
		tetraspanin_LEL	97..183	CDD:239401	18/92 (20%)
tspan8	NP_001011430.2	Tetraspanin	8..225	CDD:459767	42/219 (19%)
		TM4SF3_like_LEL	101..199	CDD:239407	26/131 (20%)