Protein Alignment Tsp42Ej and Tspan18

DIOPT Version :10

• Sequence 1: NP_523636.1
• Gene: Tsp42Ej / 35620
• FlyBaseID: FBgn0033132
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_899003.1
• Gene: Tspan18 / 241556
• MGIID: 1917186
• Length: 248
• Species: Mus musculus
• Alignment Length: 249
• Identity: 54/249 - (21%)
• Similarity: 97/249 - (38%)
• Gaps: 71/249 - (28%)

  Fly    13 GLLVTCI--LIVTCNVFFF---SC--GVTTW-------------GSAVSVYGSYGSALCGGAVFG 57
            |..::|:  |:...|.|.|   :|  ||..|             .:.:...|:|.....||.:|.
Mouse     3 GDCLSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYIVLAMGGLLFL 67

  Fly    58 VAFLGMYVALKVSYKYSIYYLICSGLVI-----AALGSYLFTFTAMREQLMGRFEERMRDLFER- 116
            :.|||...|::.:....:::.:...::.     ||:.:::|     ||.|       .|:.|.:
Mouse    68 LGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIF-----REHL-------TREFFTKE 120

  Fly   117 --KTHSDDKMQPVHS--------LFGCCGIEGPQDY--------LQEEHGALPSSCC-------- 155
              |.:..|....|.|        .|||||:.||:|:        |..:...:|.:||
Mouse   121 LTKHYQGDNDTDVFSATWNSVMITFGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRD 185

  Fly   156 ----YAFDC--SKPAHVYEEGCSTKAVATLRMQAELNYYSCMAIIALE-FLGLF 202
                ...:|  .:...:.::||.|..:.|......|.....:.::|:| ||.:|
Mouse   186 GVVLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVF 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ej	NP_523636.1	Tetraspanin	11..>135	CDD:459767	34/157 (22%)
		tetraspanin_LEL	97..183	CDD:239401	26/118 (22%)
Tspan18	NP_899003.1	Tetraspanin	10..245	CDD:459767	52/242 (21%)
		uroplakin_I_like_LEL	105..218	CDD:239409	27/124 (22%)