DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ej and Cd63

DIOPT Version :9

Sequence 1:NP_523636.1 Gene:Tsp42Ej / 35620 FlyBaseID:FBgn0033132 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_001036045.1 Gene:Cd63 / 12512 MGIID:99529 Length:238 Species:Mus musculus


Alignment Length:234 Identity:58/234 - (24%)
Similarity:97/234 - (41%) Gaps:48/234 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 KYGLLVTCILIVTCNVFFFSCGV-------------TTWGSAVSVYGSYGSALCGGAVFGVAFLG 62
            |:.|.|..:....|.|...:.||             ||.||.:.|.    ....|..:|.|||:|
Mouse    11 KFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVV----IIAVGAFLFLVAFVG 71

  Fly    63 MYVALKVSYKYSIYYLICSGLVI-----AALGSYLFTFTAMREQLMGR----FEERMRD-LFERK 117
            ...|.|.:|...|.:.|...|::     .|:..|:|     |:|:...    |:::|:: |.:.|
Mouse    72 CCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVF-----RDQVKSEFNKSFQQQMQNYLKDNK 131

  Fly   118 THSD-DKMQPVHSLFGCCGIEGPQDY-----LQEEHGALPSSCC--YAFDCS---KPAHVYEEGC 171
            |.:. ||:|..::   |||.....|:     :.::.  :|.|||  ....|.   |.:.::.:||
Mouse   132 TATILDKLQKENN---CCGASNYTDWENIPGMAKDR--VPDSCCINITVGCGNDFKESTIHTQGC 191

  Fly   172 STKAVATLRMQAELNYYSCMAIIALEFLGLFTAYHLGKA 210
            .......||....|...:.:.|..:|.||:..:..|.|:
Mouse   192 VETIAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKS 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EjNP_523636.1 Tetraspannin 11..211 CDD:278750 58/234 (25%)
tetraspanin_LEL 97..183 CDD:239401 24/101 (24%)
Cd63NP_001036045.1 Tetraspannin 10..227 CDD:395265 56/229 (24%)
CD63_LEL 105..203 CDD:239419 26/107 (24%)
Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449 234..238
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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