Protein Alignment Tsp42Ei and CD63

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_001771.1
• Gene: CD63 / 967
• HGNCID: 1692
• Length: 238
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 58/241 - (24%)
• Similarity: 100/241 - (41%)
• Gaps: 38/241 - (15%)

  Fly     4 GATTVKHVLLLLNFVFSVLGLALIAFGIFFLISAAENAVS---IGKNVAGGL----IIALGVVIL 61
            |...||.:|.:|...|....:.|||.|:     .|:..:|   |.....|.|    |||:||.:.
Human     6 GMKCVKFLLYVLLLAFCACAVGLIAVGV-----GAQLVLSQTIIQGATPGSLLPVVIIAVGVFLF 65

  Fly    62 IIAIFGCLAAIHE---APVRLLIYVGAVVLLILAQLIFLGMSSHGTKDGISGSINEGFDRLWES- 122
            ::|..||..|..|   ..:...|::..::|:.:|..|    :.:..:|.:....|..|.:..|:
Human    66 LVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAI----AGYVFRDKVMSEFNNNFRQQMENY 126

  Fly   123 -ERNQTGA-LSYYESWLQCCGVNSSEDYWIIHHGIPS---SCCPESKCMD---------TPSRVF 173
             :.|.|.: |...::..:|||..:..|:    ..|||   :..|:|.|::         ....:.
Human   127 PKNNHTASILDRMQADFKCCGAANYTDW----EKIPSMSKNRVPDSCCINVTVGCGINFNEKAIH 187

  Fly   174 KTGCKAAFVKYLDDKLLVFKIVCWLLVIGEAVGAVFGWLLYSSVKN 219
            |.||......:|...:||.......:...|.:|.||...|..|:::
Human   188 KEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	55/230 (24%)
CD63	NP_001771.1	Tetraspanin	10..229	CDD:459767	56/231 (24%)
		CD63_LEL	105..203	CDD:239419	21/101 (21%)
		Lysosomal targeting motif. /evidence=ECO:0000250|UniProtKB:P41731	234..238		58/241 (24%)