Protein Alignment Tsp42Ei and CD53

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 56/231 - (24%)
• Similarity: 105/231 - (45%)
• Gaps: 25/231 - (10%)

  Fly     1 MGLGA-TTVKHVLLLLNFVFSVLGLALIAFGIFFLIS-----AAENAVSIGKNVAGGLIIALGVV 59
            ||:.: ..:|:||...|.:|.:.|..::.|||:.||.     ...|..|:   ..|.:.:.:|.:
Human     1 MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSL---TLGNVFVIVGSI 62

  Fly    60 ILIIAIFGCLAAIHEAPVRLLIYVGAVVLLILAQL---IFLGMSSHGTKDGISGSINEGFDRLWE 121
            |:::|..||:.:|.|....|:.:...:::::||::   |.|.:......:.::..:.:...| :.
Human    63 IMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHR-YH 126

  Fly   122 SERNQTGALSYYESWLQCCGVNSSEDYWIIHHGIPSSCCPESKCMDTPSRVFKTGCKAAFVKYLD 186
            |:.:...|....:|:|||||:|.:.| |.  .|.|:||         ||.....||.|....:..
Human   127 SDNSTKAAWDSIQSFLQCCGINGTSD-WT--SGPPASC---------PSDRKVEGCYAKARLWFH 179

  Fly   187 DKLLVFKIVCWLLVIGEAVGAVFGWLLYSSVKNQSR 222
            ...|...|:...:.:.|.:|..|...|...:...|:
Human   180 SNFLYIGIITICVCVIEVLGMSFALTLNCQIDKTSQ 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	52/213 (24%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	53/214 (25%)
		CD53_like_LEL	104..186	CDD:239417	22/94 (23%)