Protein Alignment Tsp42Ei and TSPAN18

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 53/260 - (20%)
• Similarity: 96/260 - (36%)
• Gaps: 69/260 - (26%)

  Fly     8 VKHVLLLLNFVFSVLGLALIAFGIFFLISAAENAVSIGKN---VAGG-LIIALGVVILIIAIFGC 68
            :|:::.:.||...:.|..|:|.||:.::........:..|   :.|. :::|:|.::.::...||
Human    19 MKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFLLGFLGC 83

  Fly    69 LAAIHEAPVRLLIYVGAVVLLILAQL-------IF------------LGMSSHGTKDGISGSINE 114
            ..|:.|....||.:...::::.||:|       ||            |.....|..|      .:
Human    84 CGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHYQGNND------TD 142

  Fly   115 GFDRLWESERNQTGALSYYESWLQCCGVNSSEDY---------WIIHHGIPSSCC---PESK--- 164
            .|...|.|.....|          |||||..||:         .:....:|.:||   |:|:
Human   143 VFSATWNSVMITFG----------CCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRDGV 197

  Fly   165 ------CMDTPSRVF-KTGCKAAFVKYLDDKLLVFKIVCWLLVIG----EAVGAVFGWLLYSSVK 218
                  |:...|... |.||....:...:    .:..:...|.||    |....:|...|:..::
Human   198 LLSREECLLGRSLFLNKQGCYTVILNTFE----TYVYLAGALAIGVLAIELFAMIFAMCLFRGIQ 258

  Fly   219  218
            Human   259  258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	52/254 (20%)
TSPAN18	XP_005253274.1	Tetraspanin	20..255	CDD:459767	53/254 (21%)
		uroplakin_I_like_LEL	115..228	CDD:239409	26/132 (20%)