Protein Alignment Tsp42Ei and TSPAN7

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 62/242 - (25%)
• Similarity: 107/242 - (44%)
• Gaps: 59/242 - (24%)

  Fly     6 TTVKHVLLLLNFVFSVLGLALIAFGIF-------FLISAAENAVSIGKNVAGGLIIALGVVILII 63
            |.:|.:|::.:|||.:.|:.|:|.|::       ::...|||:.:     |..::|..|..|::.
Human    13 TCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTN-----APYVLIGTGTTIVVF 72

  Fly    64 AIFGCLAAIHEAPVRLLIYVGAVVLLILAQLIFLGMSSHGTKDGISG-----SINEGFDRLW--- 120
            .:|||.|....:|..|.:|...:.|:.||:|:          .||||     .|.:.|.|.:
Human    73 GLFGCFATCRGSPWMLKLYAMFLSLVFLAELV----------AGISGFVFRHEIKDTFLRTYTDA 127

  Fly   121 ------ESERNQTGALSYYESWLQCCGV----NSSEDYWIIHHGIPSSCC-PESKCMD------- 167
                  ..||::  |:.:.:..|.||||    |.|...:.:.||||.||| .|:.|..
Human   128 MQTYNGNDERSR--AVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLT 190

  Fly   168 -TPSRVFKTGCKAAFVKYLDDKLLVFKIVCWLLVIGEAVGAVFGWLL 213
             ..::|.:.||......:::..:.:        :.|.|.|..|..|:
Human   191 VAATKVNQKGCYDLVTSFMETNMGI--------IAGVAFGIAFSQLI 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	61/240 (25%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	61/240 (25%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	25/104 (24%)