Protein Alignment Tsp42Ei and TSPAN33

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 62/248 - (25%)
• Similarity: 110/248 - (44%)
• Gaps: 37/248 - (14%)

  Fly     8 VKHVLLLLNFVFSVLGLALIAFGIFF-LISAAENAVSIGKNVAGGLIIALGVVILIIAIFGCLAA 71
            ||::|...|.:|.|:.:.::|.|::. |:..||.|::........|:|.:||::.::...||:.:
Human    22 VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGCIGS 86

  Fly    72 IHEAPVRLLIY---VGAVVLLILAQLIFLGMSSHGTKDGISGSINEGFDRLWESERNQTGALSYY 133
            :.|....|..:   :.||.||.||..|...:.|...:..:|..||..... :..:.:....:.:.
Human    87 LRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVH-YRDDLDLQNLIDFG 150

  Fly   134 ESWLQCCGVNSSED-----YWIIHHGIPS--SC-CPESKCMDTPSR-VFKTGC---KAAFVKYLD 186
            :....|||..|.:|     |:......||  .| .|.|.|:.||.: |..|.|   ..|| .||:
Human   151 QKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINTMCGQGMQAF-DYLE 214

  Fly   187 DKLLVF------KIVCWL-------------LVIGEAVGAVFGWLLYSSVKNQ 220
            ...:::      |:|.|:             |.|.:.||.:...:|.:.:|:|
Human   215 ASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIKDQ 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	59/240 (25%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	60/241 (25%)
		penumbra_like_LEL	116..236	CDD:239411	28/121 (23%)