Protein Alignment Tsp42Ei and TSPAN17

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 49/227 - (21%)
• Similarity: 89/227 - (39%)
• Gaps: 51/227 - (22%)

  Fly     9 KHVLLLLNFVFSVLGLALIAFGIFFLISAAENAVSIGKNVA-----GG-----LIIALGVVILII 63
            |:.|...|.||.|||...:|.|::     |.....:..|::     ||     |.:.:|.|:.::
Human    18 KYFLFGFNIVFWVLGALFLAIGLW-----AWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77

  Fly    64 AIFGCLAAIHEAPVRL---LIYVGAVVLLILAQLIFLGMSSHGTKDGISGSINEGFDRLWESERN 125
            ...||:.|:.|....|   .:::|.:..|.||..|...:.....:|.::..||... :.:..:.:
Human    78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV-KAYRDDID 141

  Fly   126 QTGALSYYESWLQCCGVNSSEDYWIIH--------------HGIPSSCCP--------ESKC--- 165
            ....:.:.:.:..|||.....| |.::              .|:|.|||.        .::|
Human   142 LQNLIDFAQEYWSCCGARGPND-WNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYD 205

  Fly   166 ------MDTPSRVFKTGCKAAFVKYLDDKLLV 191
                  ::....:...||...|.|:|.|.|:|
Human   206 VRLKLELEQQGFIHTKGCVGQFEKWLQDNLIV 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	49/227 (22%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	31/144 (22%)
		TM4SF9_like_LEL	115..235	CDD:239412	20/121 (17%)