DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ei and tsp-16

DIOPT Version :10

Sequence 1:NP_523635.2 Gene:Tsp42Ei / 35618 FlyBaseID:FBgn0033130 Length:229 Species:Drosophila melanogaster
Sequence 2:NP_509183.2 Gene:tsp-16 / 192066 WormBaseID:WBGene00006642 Length:311 Species:Caenorhabditis elegans


Alignment Length:247 Identity:56/247 - (22%)
Similarity:88/247 - (35%) Gaps:80/247 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 VKHVLLLLNFVFSVLGLA-LIAFGIFFLISAAENAVSIGKNVAGGLIIALGVVILIIAIFGCLAA 71
            :|..|.||..|.:::|.. ::.|||..|...:..|..||.|    ||:....:::::.|...:. 
 Worm    17 LKKCLALLLSVLTMIGSGFIVGFGIQTLREVSFTASVIGTN----LIVYCPYLLILVGILSFVM- 76

  Fly    72 IHEAPVR-----------LLIYVGAVVLL--ILAQLIFLG------MSSHGTKDGISGSINEGFD 117
               .|||           ::.::.|.:..  |.|....||      :||...:..:..||.|.:.
 Worm    77 ---TPVRFFSIILNDNKIMITHMFATIFFATICAMTAILGYDLNSHVSSSDMEHWMKHSIKEDYG 138

  Fly   118 RLWESERNQTGALSYYESW------LQCCGVNSSEDY----WII------HHGIPSSCCPESKCM 166
                   |.| |....|.|      .:||||.:..|:    |.|      ...||.|||.....|
 Worm   139 -------NPT-APHIMEEWNKAHRQFKCCGVRNLTDFVESKWYIMQKKHPRQRIPDSCCASCATM 195

  Fly   167 -------------DTPSRVFK---------TGCKAAFVKYLDDKLLVFKIVC 196
                         :.|.::.|         .||.:|      |..:..:.||
 Worm   196 HERFCVAFFKEPGNQPHQLVKNQTICLQASNGCLSA------DSSIANREVC 241

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EiNP_523635.2 Tetraspanin 8..214 CDD:459767 56/247 (23%)
tsp-16NP_509183.2 Tetraspanin 26..174 CDD:459767 37/163 (23%)
uroplakin_I_like_LEL 118..210 CDD:239409 23/99 (23%)

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