Protein Alignment Tsp42Ei and Tspan8

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_598210.1
• Gene: Tspan8 / 171048
• RGDID: 621783
• Length: 235
• Species: Rattus norvegicus
• Alignment Length: 232
• Identity: 58/232 - (25%)
• Similarity: 111/232 - (47%)
• Gaps: 29/232 - (12%)

  Fly     8 VKHVLLLLNFVFSVLGLALIAFGIFFLISA-AENAVSIGKN-----VAGGLIIALGVVILIIAIF 66
            :|:.:...||:|.|.|..::...|:..:|. .:..::.|.|     :|..::||:|.:|:::...
  Rat     8 LKYSMFFFNFLFWVCGTLILGLAIWLRVSKDGKEIITSGDNGTNPFIAVNILIAVGSIIMVLGFL 72

  Fly    67 GCLAAIHEAPVRLLIYVGAVVLLILAQLIFLGMSSHGTKDGISGSINEGFDRLWESER--NQTG- 128
            ||..|:.|:...||::...::|::|.| :..|:.....|...|..:||   .|:|:.:  ::|.
  Rat    73 GCCGAVKESRCMLLLFFIGLLLILLLQ-VAAGILGATFKSESSRILNE---TLYENAKLLSETSN 133

  Fly   129 -------ALSYYESWLQCCGVNSSEDYWIIHHGIP---SSC-CPESKCMD-TPSRVFKTGCKAAF 181
                   |:..::|..:|||:......|  ....|   .|| |..|.|.. ....|::|.| .:.
  Rat   134 EAKEVQKAMIAFQSEFKCCGLRFGAADW--GKNFPDAKESCQCTGSDCESYNGENVYRTTC-LSL 195

  Fly   182 VKYLDDKLLVFKI-VCWLLVIGEAVGAVFGWLLYSSV 217
            :|.|.:|.::..| :.:.|.:.|.:|.||..:||..:
  Rat   196 IKELVEKNIIIVIGIAFGLAVIEILGLVFSMVLYCQI 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	56/227 (25%)
Tspan8	NP_598210.1	Tetraspanin	8..230	CDD:459767	57/228 (25%)
		TM4SF3_like_LEL	106..204	CDD:239407	25/103 (24%)