Protein Alignment Tsp42Ei and TSPAN19

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_001094387.1
• Gene: TSPAN19 / 144448
• HGNCID: 31886
• Length: 248
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 57/265 - (21%)
• Similarity: 98/265 - (36%)
• Gaps: 85/265 - (32%)

  Fly     8 VKHVLLLLNFVFSVLGLALIAFGIFFLISAAENAVSIGKN-----VAGGLIIALGVVILIIAIFG 67
            :|:.|.|:|..|.||||..:.||.:.|:.......:..:|     ....::|.:|...::..:.|
Human    10 IKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFIVPISQILIGMGSSTVLFCLLG 74

  Fly    68 CLAAIHEAPVRLLIYVGAVVL-------LILAQLIFLGMSSHGTKDGISGSINEGFDRLWESERN 125
            .:...:|  :|.|:.|.||::       ::|:..|.       ||       .|...:||..:.:
Human    75 YIGIHNE--IRWLLIVYAVLITWTFAVQVVLSAFII-------TK-------KEEVQQLWHDKID 123

  Fly   126 QTGALSYYES---------W---------LQCCGVNSSEDYWIIHHG------IPSSCCPESK-- 164
              ..:|.|.|         |         |||||.::..| ||.:..      :|.||...:.
Human   124 --FVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTD-WIKNKNKENSGQVPCSCTKSTLRK 185

  Fly   165 --CMDTPSRVFKTGCKAAFVKYLDDKLLVFKIVCWLLV-IGEAVGAVFGWL------------LY 214
              |.:..:..:..||:.             ||..|..| :...:|..||.|            .:
Human   186 WFCDEPLNATYLEGCEN-------------KISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFF 237

  Fly   215 SSVKN 219
            .::||
Human   238 KNIKN 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	55/258 (21%)
TSPAN19	NP_001094387.1	Tetraspanin	10..>155	CDD:459767	36/162 (22%)
		CD37_CD82_like_LEL	107..212	CDD:239413	28/134 (21%)