Protein Alignment Tsp42Ei and UPK1A

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 47/224 - (20%)
• Similarity: 87/224 - (38%)
• Gaps: 58/224 - (25%)

  Fly     4 GATTVKHVLLLLNFVFSVLGLALIAFGIFFLISAAE------NAVSIGKNVAGGLIIAL--GVVI 60
            |:..|..:|::.|.:..:.||:|.|..|:  ::|.:      ..||...:|..|..||:  |...
Human    13 GSPVVVGLLVVGNIIILLSGLSLFAETIW--VTADQYRVYPLMGVSGKDDVFAGAWIAIFCGFSF 75

  Fly    61 LIIAIFGCLAAIHEAPVRLLIYVGAVVLLILAQLIFL-----GMSSHGTKDGI------------ 108
            .::|.||..||:......:|.|      |:|..::::     .::|:..:|.:
Human    76 FMVASFGVGAALCRRRSMVLTY------LVLMLIVYIFECASCITSYTHRDYMVSNPSLITKQML 134

  Fly   109 ---SGSINEG--FDRLWESERNQTGALSYYESWLQCCGVNSSEDYWIIHHGIPSSCCPESK---- 164
               |...::|  ..|||:....:.          :|||.:...| |:.......:..||..
Human   135 TFYSADTDQGQELTRLWDRVMIEQ----------ECCGTSGPMD-WVNFTSAFRAATPEVVFPWP 188

  Fly   165 ---CMDTPSRV--FKTGCKAAFVKYLDDK 188
               |..|.:.:  .:.||:...:.||..|
Human   189 PLCCRRTGNFIPLNEEGCRLGHMDYLFTK 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	46/220 (21%)
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	32/155 (21%)
		uroplakin_I_like_LEL	113..231	CDD:239409	21/116 (18%)