Protein Alignment Tsp42Ei and TSPAN5

DIOPT Version :10

• Sequence 1: NP_523635.2
• Gene: Tsp42Ei / 35618
• FlyBaseID: FBgn0033130
• Length: 229
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 56/265 - (21%)
• Similarity: 106/265 - (40%)
• Gaps: 55/265 - (20%)

  Fly     8 VKHVLLLLNFVFSVLGLALIAFGIFFLISAAENAVSIGKNVA-----GG-----LIIALGVVILI 62
            :|:.:...|.:|..||:..:..|::     |.|...:..|::     ||     |.:.:|.|:.|
Human    15 IKYFIFGFNVIFWFLGITFLGIGLW-----AWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFI 74

  Fly    63 IAIFGCLAAIHEAPVRL---LIYVGAVVLLILAQLIFLGMSSHGTKDGISGSINEGFDRLWESER 124
            :...||:.|:.|....|   .:::|.:..|.|...:...:.....||.:...||... |.:..:.
Human    75 LGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNI-RAYRDDI 138

  Fly   125 NQTGALSYYESWLQCCGVNSSEDYWIIH--------------HGIPSSCCPE--------SKC-- 165
            :....:.:.:.:.||||...::| |.::              .|:|.|||.:        ::|
Human   139 DLQNLIDFTQEYWQCCGAFGADD-WNLNIYFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGY 202

  Fly   166 -------MDTPSRVFKTGCKAAFVKYLDDKLLVFKIVCWLLVIGEAVGAVFGWLLYSSVKNQSRR 223
                   :|....::..||...|.|:|.|.|.:...:    .||.|:..:||..|..::.:....
Human   203 DARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGI----FIGIALLQIFGICLAQNLVSDIEA 263

  Fly   224 NNAVW 228
            ..|.|
Human   264 VRASW 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ei	NP_523635.2	Tetraspanin	8..214	CDD:459767	53/249 (21%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	54/253 (21%)
		TM4SF9_like_LEL	113..233	CDD:239412	24/121 (20%)