DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Eh and CD53

DIOPT Version :9

Sequence 1:NP_523634.1 Gene:Tsp42Eh / 35617 FlyBaseID:FBgn0033129 Length:231 Species:Drosophila melanogaster
Sequence 2:NP_000551.1 Gene:CD53 / 963 HGNCID:1686 Length:219 Species:Homo sapiens


Alignment Length:227 Identity:55/227 - (24%)
Similarity:100/227 - (44%) Gaps:54/227 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 RLLRYVLCVISGICALGGCLLIWYGAWL------------LDSLSEEQRMLGMDHGEDLAAVLCV 58
            :||:|||...:.:..:.||.::.:|.:|            |.||:     ||.         :.|
Human     7 KLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLT-----LGN---------VFV 57

  Fly    59 LLGTVIVVASIFGSVAVAKDSRVLLICYAVLLVFLLIVQIVLVSISYAASRDFLPDSLRQGLDDL 123
            ::|::|:|.:..|.:...|:::.||:.:.:||:.:|:.::.|..:.:...:. |.:.:.:||.|.
Human    58 IVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQK-LNEYVAKGLTDS 121

  Fly   124 WDLQHEGNST---LNTYEEWLHCCGRNSAEDYLHLEKMPPPSCCLNRDCTKHLNLFMTGCEVKFK 185
            ....|..|||   .::.:.:|.|||.|...|:   ...||.||..:|.        :.||..|.:
Human   122 IHRYHSDNSTKAAWDSIQSFLQCCGINGTSDW---TSGPPASCPSDRK--------VEGCYAKAR 175

  Fly   186 EYVGAKTANFHSLSWFLVIFEFAGSVTTCYLV 217
                         .||...|.:.|.:|.|..|
Human   176 -------------LWFHSNFLYIGIITICVCV 194

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EhNP_523634.1 Tetraspannin 8..220 CDD:278750 54/225 (24%)
tetraspanin_LEL 109..192 CDD:239401 22/85 (26%)
CD53NP_000551.1 Tetraspannin 9..206 CDD:366035 54/225 (24%)
CD53_like_LEL 104..186 CDD:239417 25/106 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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