Protein Alignment Tsp42Eh and TSPAN6

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 58/246 - (23%)
• Similarity: 96/246 - (39%)
• Gaps: 50/246 - (20%)

  Fly    11 VLCVISGICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLLGTVIVVASIFGSVAV 75
            ||.:.:.|..:.|.:|:..|.|...||.....:|. :...::..|| :..||||::...||..|.
Human    20 VLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLN-EKATNVPFVL-IATGTVIILLGTFGCFAT 82

  Fly    76 AKDSRVLLICYAVLLVFLLIVQIVLVSISYAASRDFLPDSLRQGLDDLWDLQHE-GNSTLNTYEE 139
            .:.|..:|..||:.|..:.:|::|...:.:.                   .:|| .||..|.||:
Human    83 CRASAWMLKLYAMFLTLVFLVELVAAIVGFV-------------------FRHEIKNSFKNNYEK 128

  Fly   140 ---------------------WLHCCGRNSAEDY----LHLEKMPPPSCCLNRDCTKHLN---LF 176
                                 .|||||.....|:    .:.||..|.|||...|||...:   :.
Human   129 ALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVN 193

  Fly   177 MTGCEVKFKEYVGAKTANFHSLSWFLVIFEFAGSVTTCYLVDSIRNHRDRI 227
            ..||.:|....:.::......:|:.:..|:..|......|..:|.|::..|
Human   194 NEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEI 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	54/234 (23%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	55/235 (23%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	25/115 (22%)