DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Eh and TSPAN8

DIOPT Version :9

Sequence 1:NP_523634.1 Gene:Tsp42Eh / 35617 FlyBaseID:FBgn0033129 Length:231 Species:Drosophila melanogaster
Sequence 2:NP_001356689.1 Gene:TSPAN8 / 7103 HGNCID:11855 Length:237 Species:Homo sapiens


Alignment Length:230 Identity:47/230 - (20%)
Similarity:103/230 - (44%) Gaps:16/230 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LRYVLCVISGICALGGCLLIWYGAWLLDSLSEEQRMLGM-DHGED--LAAVLCVLLGTVIVVASI 69
            ::|.:...:.:..|.|.|::....|:..| ::.|.:.|. |.|..  :|..:.:.:|.:|::...
Human     8 IKYSMFTFNFLFWLCGILILALAIWVRVS-NDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGF 71

  Fly    70 FGSVAVAKDSRVLLICYAVLLVFLLIVQI---VLVSISYAASRDFLPDSLRQG---LDDLWDLQH 128
            .|.....|:||.:|:.:.:.|:.:|::|:   :|.::..:.|...:.::|.:.   |....:.:.
Human    72 LGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYENTKLLSATGESEK 136

  Fly   129 EGNSTLNTYEEWLHCCGR-NSAEDY-LHLEKMPPPSCCLN--RDCTKH--LNLFMTGCEVKFKEY 187
            :....:..::|...|||. |.|.|: .:.:..|....||:  |.|..:  ..::...|....|::
Human   137 QFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQRPCQSYNGKQVYKETCISFIKDF 201

  Fly   188 VGAKTANFHSLSWFLVIFEFAGSVTTCYLVDSIRN 222
            :.........:|:.|.:.|..|.|.:..|...|.|
Human   202 LAKNLIIVIGISFGLAVIEILGLVFSMVLYCQIGN 236

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EhNP_523634.1 Tetraspannin 8..220 CDD:278750 45/226 (20%)
tetraspanin_LEL 109..192 CDD:239401 16/91 (18%)
TSPAN8NP_001356689.1 Tetraspannin 8..230 CDD:334016 44/222 (20%)
TM4SF3_like_LEL 106..206 CDD:239407 17/99 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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