Protein Alignment Tsp42Eh and TSPAN7

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 52/229 - (22%)
• Similarity: 95/229 - (41%)
• Gaps: 26/229 - (11%)

  Fly     8 LRYVLCVISGICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLLGTVIVVASIFGS 72
            |:.:|.:.|.:..:.|.:|:..|.|...:|.....::.  .....|..:.:..||.|||..:||.
Human    15 LKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIA--ENSTNAPYVLIGTGTTIVVFGLFGC 77

  Fly    73 VAVAKDSRVLLICYAVLLVFLLIVQIVLVSISYAASRDFLPDS-LRQGLDDL--WDLQHEGNSTL 134
            .|..:.|..:|..||:.|..:.:.::| ..||....|..:.|: ||...|.:  ::...|.:..:
Human    78 FATCRGSPWMLKLYAMFLSLVFLAELV-AGISGFVFRHEIKDTFLRTYTDAMQTYNGNDERSRAV 141

  Fly   135 NTYEEWLHCCGRNSAEDYLHLEKMP-------PPSCCLNR-DCT----KHLNLFMT-----GCEV 182
            :..:..|.|||   .::|.:....|       |||||:|. ||.    .:|.:..|     ||..
Human   142 DHVQRSLSCCG---VQNYTNWSTSPYFLEHGIPPSCCMNETDCNPQDLHNLTVAATKVNQKGCYD 203

  Fly   183 KFKEYVGAKTANFHSLSWFLVIFEFAGSVTTCYL 216
            ....::.........:::.:...:..|.:..|.|
Human   204 LVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCL 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	52/229 (23%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	52/229 (23%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	24/105 (23%)