Protein Alignment Tsp42Eh and Tspan15

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_001108504.1
• Gene: Tspan15 / 679462
• RGDID: 1588304
• Length: 294
• Species: Rattus norvegicus
• Alignment Length: 257
• Identity: 59/257 - (22%)
• Similarity: 117/257 - (45%)
• Gaps: 51/257 - (19%)

  Fly     8 LRYVLCVISGICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLLGTVIVVASIFGS 72
            |::.|.:.|.:..|.|.|::..|.:   :.:|.|:...::......|::.:|||.|:.:.|..|.
  Rat    20 LKFSLIIYSTVFWLIGGLVLSVGIY---AEAERQKYKTLESAFLAPAIILILLGVVMFIVSFIGV 81

  Fly    73 VAVAKDSRVLLICYAVLLVFLLIVQIV--LVSISYA-ASRDFLPDSLRQGLDDLWDLQHEGNSTL 134
            :|..:|:..||..:..:|...|:::::  :|::.:. .:.|||.|::|:|:::.:| ..:..:.:
  Rat    82 LASLRDNLCLLQSFMFILGLCLVMELIGGIVALIFRNQTIDFLNDNIRRGIENYYD-DLDFKNIM 145

  Fly   135 NTYEEWLHCCGRNSAEDYLHLEK-------MPPP-------SCCLNRDCTKHLNLFMTGCEVKFK 185
            :..::...|||   .|||....|       .|.|       :||: |:.|..:|. |.|.:...|
  Rat   146 DFVQKKFKCCG---GEDYRDWSKNQYHDCSAPGPLACGVPYTCCI-RNTTDVVNT-MCGYKTIDK 205

  Fly   186 EYVGAKTANFH-------SLSWF-------------LVIFEFAGSVTTCYLV----DSIRNH 223
            |.:.|:.. .|       .|.||             :::.:|.|.:.|...:    |.|..|
  Rat   206 ERLNAQNI-IHVRGCTNAVLIWFMDNYSIMAGLLLGILLPQFLGVLLTLLYITRVEDIILEH 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	56/245 (23%)
Tspan15	NP_001108504.1	Tetraspanin	20..>157	CDD:459767	33/143 (23%)
		penumbra_like_LEL	114..231	CDD:239411	30/123 (24%)