DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Eh and Tspan1

DIOPT Version :9

Sequence 1:NP_523634.1 Gene:Tsp42Eh / 35617 FlyBaseID:FBgn0033129 Length:231 Species:Drosophila melanogaster
Sequence 2:NP_598442.1 Gene:Tspan1 / 66805 MGIID:1914055 Length:240 Species:Mus musculus


Alignment Length:249 Identity:57/249 - (22%)
Similarity:105/249 - (42%) Gaps:37/249 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MYCTTRLLRYVLCVISGICALGGCLLIWYGAWL-LDSLS--------EEQRMLGMDHGEDLAAVL 56
            |.| .:.::.::.:.:.:..|.|..|:..|.|: :|..|        ....|..::.|..|.|. 
Mouse     1 MQC-FKFIKVMMFLFNLLIFLCGAALLAVGIWVSVDGTSFLKVFGSLSSSAMQFVNVGYFLIAA- 63

  Fly    57 CVLLGTVIVVASIFGSVAVAKDSRVLLICYAVLLVFLLIVQI--VLVSISYAA-SRDFLPDSLRQ 118
                |.|:.:....|......:::.:|:.:..:|:.:.|.:|  .:|::.|.. :..||...:..
Mouse    64 ----GAVLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTLAEQFLTLLVVP 124

  Fly   119 GLDDLWDLQHEGNSTLNTYEEWLHCCGRNSAED-----YLHLEKMPPPSCCLN------RDCT-- 170
            .::..:..|.:.....||..|.|||||.|:..|     ::...|:.||.||.|      ..||  
Mouse   125 AIEKDYGYQTDFTQVWNTTMEELHCCGFNNYTDFNASRFVKENKVFPPPCCANPGNHTVEPCTEE 189

  Fly   171 KHLNLFMTGCEVKFKEYVGAKTANFHSLSWFLV---IFEFAGSVTTCYLVDSIR 221
            |..::.:.||   |||.:....||..::....|   ..|.|..|.:.||..:::
Mouse   190 KAKSMKVQGC---FKEILHRIRANAVTVGGVAVGVAALELAAMVVSMYLYCNLK 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EhNP_523634.1 Tetraspannin 8..220 CDD:278750 55/239 (23%)
tetraspanin_LEL 109..192 CDD:239401 27/95 (28%)
Tspan1NP_598442.1 Tetraspannin 7..235 CDD:366035 53/235 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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