Protein Alignment Tsp42Eh and Tspan14

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_666040.1
• Gene: Tspan14 / 52588
• MGIID: 1196325
• Length: 270
• Species: Mus musculus
• Alignment Length: 205
• Identity: 49/205 - (23%)
• Similarity: 93/205 - (45%)
• Gaps: 41/205 - (20%)

  Fly    15 ISGICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLLGTVIVVASIFGSVAVAKDS 79
            ::|:..||..|..|....:|..|::..|:.|:|     ..||.:::|.|:......|.|...:::
Mouse    28 LAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGID-----PVVLVLMVGVVMFTLGFAGCVGALREN 87

  Fly    80 RVLL--ICYAVLLVFLLIVQIVLVSISYA-----ASRDFLPDSLRQGLDDLWDLQHEGNSTLNTY 137
            ..||  .|.|::|:|.|.:.:.:::..:.     ..|:|...:::...||: |||    :.:::.
Mouse    88 ICLLKFFCGAIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDI-DLQ----NLIDSL 147

  Fly   138 EEWLHCCGRNSAEDY-LHL-----------EKMPPP-SCCLNRDCTKHLNLFMTGC--------E 181
            ::...|||....||: |::           ||...| |||:.....|.:|   |.|        :
Mouse   148 QKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVN---TQCGYDVRIQLK 209

  Fly   182 VKFKEYVGAK 191
            .|:.|::..|
Mouse   210 SKWDEFIFTK 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	49/205 (24%)
Tspan14	NP_666040.1	Tetraspanin	16..258	CDD:459767	49/205 (24%)
		TM4SF9_like_LEL	113..233	CDD:239412	26/115 (23%)
		Necessary and sufficient for interaction with ADAM10. /evidence=ECO:0000250|UniProtKB:Q8NG11	114..232		26/114 (23%)