Protein Alignment Tsp42Eh and TSPAN33

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 51/270 - (18%)
• Similarity: 114/270 - (42%)
• Gaps: 61/270 - (22%)

  Fly     7 LLRYVLCVISGICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGED----LA---AVLCVLLGTVI 64
            |::|:|...:        :|.|..:.::.::....|:  |.|.|.    ||   |:|.:::|.::
Human    21 LVKYLLFFFN--------MLFWVISMVMVAVGVYARL--MKHAEAALACLAVDPAILLIVVGVLM 75

  Fly    65 VVASIFGSVAVAKDSRVLLICYAVLLVFLLIVQIVLVSISYAAS-------RDFLPDSLRQGLDD 122
            .:.:..|.:...:::..||..:::.|..:.::|:....:.:..|       .:.:.:::....||
Human    76 FLLTFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDD 140

  Fly   123 LWDLQHEGNSTLNTYEEWLHCCGR------------NSAEDYLHLEKMPPP-SCCL--------N 166
            | |||    :.::..::...|||.            |.:||....|:...| ||||        |
Human   141 L-DLQ----NLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVIN 200

  Fly   167 RDCTKHLN----------LFMTGCEVKFKEYVGAKTANFHSLSWFLVIFEFAGSVTTCYLVDSIR 221
            ..|.:.:.          ::..||..|...::.:.......::..|.|.:..|.:.:..||:.|:
Human   201 TMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIK 265

  Fly   222 NHRDRIRFYN 231
            : :.:::.||
Human   266 D-QIKLQLYN 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	45/253 (18%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	46/254 (18%)
		penumbra_like_LEL	116..236	CDD:239411	24/124 (19%)