Protein Alignment Tsp42Eh and Prph2

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_037153.1
• Gene: Prph2 / 25534
• RGDID: 3549
• Length: 346
• Species: Rattus norvegicus
• Alignment Length: 284
• Identity: 57/284 - (20%)
• Similarity: 104/284 - (36%)
• Gaps: 75/284 - (26%)

  Fly    12 LCVISGICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLLGTVIVVASIFGSVA-- 74
            |.:::.:..|.|.:|...|.:|...|.:...:  ||:.|. ..|...|:| |.|::.:|.|:|
  Rat    20 LWLMNWLSVLAGIVLFSLGLFLKIELRKRSDV--MDNSES-HFVPNSLIG-VGVLSCVFNSLAGK 80

  Fly    75 VAKDS---------RVLLICYAVLLVFLLIVQIVLVSISYAASRDFLPDSLRQGLDD----LWDL 126
            :..|:         :..|..|..:.||..:: :.||::.....|..|..:|..||.:    ..|.
  Rat    81 ICYDALDPAKYAKWKPWLKLYLAVCVFFNVI-LFLVALCCFLLRGSLESTLAYGLKNGMKYYRDT 144

  Fly   127 QHEG----NSTLNTYEEWLHCCGRNSAEDYLHLEKMP---------------------------- 159
            ...|    ..|::..:....|||.|...|:..::.:.
  Rat   145 DTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGV 209

  Fly   160 PPSCC---LNRDC-----------------TKHLNLFMTGCEVKFKEYVGAKTANFHSLSWFLVI 204
            |.|||   ..|.|                 |:.|||::.||......|..:...:...::..:.:
  Rat   210 PFSCCNPSSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLNYYSSLMNSMGVVTLLIWL 274

  Fly   205 FEFAGSVTTCYL---VDSIRNHRD 225
            ||.:.:....:|   ::|:.|..|
  Rat   275 FEVSITAGLRFLHTALESVSNPED 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	54/274 (20%)
Prph2	NP_037153.1	Tetraspanin	16..181	CDD:459767	38/165 (23%)
		peripherin_like_LEL	120..262	CDD:239415	26/141 (18%)
		Interaction with MREG. /evidence=ECO:0000250	341..346