Protein Alignment Tsp42Eh and TSPAN19

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_001094387.1
• Gene: TSPAN19 / 144448
• HGNCID: 31886
• Length: 248
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 61/252 - (24%)
• Similarity: 108/252 - (42%)
• Gaps: 50/252 - (19%)

  Fly     5 TRLLRYVLCVISGICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLL---GTVIVV 66
            |.:::|.|.:|:|...:.|.|.:.:|||||  |.....:...|........:..:|   |:..|:
Human     7 TIIIKYFLNLINGAFLVLGLLFMGFGAWLL--LDRNNFLTAFDENNHFIVPISQILIGMGSSTVL 69

  Fly    67 ASIFGSVAVAKDSRVLLICYAVLLVFLLIVQIVLVS--------------------ISYAASRDF 111
            ..:.|.:.:..:.|.|||.||||:.:...||:||.:                    ||...|:|
Human    70 FCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEYGSKD- 133

  Fly   112 LPDSLRQGLDDLWDLQHEGNSTLNTYEEWLHCCGRNSAEDYLHLEK-----MPPPSCCLNR---- 167
            .|:.:.:     |.:       ||..::.|.|||:::..|::..:.     ..|.||..:.
Human   134 KPEDITK-----WTI-------LNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKSTLRKW 186

  Fly   168 DCTKHLN-LFMTGCEVKFKEYVGAKTANFHSLSWFLVIFE-FAGSVTTCYLVDSIRN 222
            .|.:.|| .::.|||.|...:..........:::.|:..| |..|:|.|:. .:|:|
Human   187 FCDEPLNATYLEGCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFF-KNIKN 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	58/242 (24%)
TSPAN19	NP_001094387.1	Tetraspanin	10..>155	CDD:459767	39/159 (25%)
		CD37_CD82_like_LEL	107..212	CDD:239413	23/117 (20%)